BDBM19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317
SMILES OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F
InChI Key InChIKey=SGIWFELWJPNFDH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 19993
Affinity DataKi: 132nMAssay Description:Binding affinity to RORa (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inverse agonist activity at human ROR-alpha1 expressed in HEK293 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.01E+3nMAssay Description:Inverse agonist activity at RORalpha (unknown origin) by M1H assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of RORa (unknown origin) assessed as inhibition of coactivator recruitment by GAL4-nuclear receptor LBD assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Agonist activity at RoRa (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 NR reporter cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Inverse agonist activity at GAL4-fused human RORa expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human RORalpha1 expressed in HEK293 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inverse agonist activity at Gal4-fused RORalpha LBD (unknown origin) expressed in 293T cells measured after 24 hrs by dual-luciferase reporter gene a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human GAL4-fused RORalpha LBD transfected in HEK293T cell measured after 24 hrs by luciferase reporter assayMore data for this Ligand-Target Pair